Summary
The myelin sheath, which wraps around axons, is crucial for proper nerve conduction. Myelin loss contributes to various neurological disorders, including multiple sclerosis (MS) and neuromyelitis optica (NMO). IPG017 is a novel small molecule antagonist that enhances the differentiation and maturation of oligodendrocyte progenitor cells ( OPCs) into mature oligodendrocytes, promoting myelin regeneration. It holds great potential as a treatment for neuro-demyelinating diseases.
Mechanism of Action
Demyelination disrupts nerve conduction and leads to axonal degeneration, resulting in physical disabilities; IPG017 facilitates the differentiation of OPCs into mature oligodendrocytes, restoring neural myelination and improving overall function.
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